The 34-year-old has had a relatively successful first year at Old Trafford, scoring six goals and two assists from 19 games in the Premier League.
However, it has been suspected for some time that the Uruguayan international could be tempted to return to South America after 14 years in Europe.
According to ESPN, the veteran is currently expected to sign a deal with Argentine giants Boca Juniors in the coming months.
While Cavani has a two-year deal with United, Both parties can also agree to cut ties in the summer.
Luis Cavani, Edinson’s father, has previously suggested that his son would sign for Boca Juniors rather than stay in England.